DataFrame I have:
A B C 2012-01-01 1 2 3 2012-01-05 4 5 6 2012-01-10 7 8 9 2012-01-15 10 11 12
What
Couldn't resist answering this, even though the question was asked, and answered, in 2012, by Wes himself, and again in 2015, by ajsp. Yes, besides 'truncate', you can also use get_loc with the option 'nearst'
df.iloc[df.index.get_loc(datetime.datetime(2016,02,02),method='nearest')]