The solution works great with cassini but as soon as I make it run into IIS (7.5 on Windows 7 / 64), it stops working. All js & css file are never downloaded and the script fails. I looked into the MiniProfilerHanler, the GetHttpHandler method is called for each required js & css but the ProcessRequest method never runs.
The same behavior is observed using the sample.mvc project that goes along with the mini profiler sources.
this is an older question but if you are still trying to get this to work try adding this to your web.config
<system.webServer>
<modules runAllManagedModulesForAllRequests="true"/>
</system.webServer>
not really the best solution but it works
I went to Program/Feature control pannel and clicked add remove windows feature. There I saw that under IIS, ASP.Net was not selected (all my sites worked like a charm) and checked it.. and Voila ! Don't ask ;-)
来源：https://stackoverflow.com/questions/6555533/mvc-mini-profiler-1-4-iis