Currently, in the Android Studio version 3.3, the shortcut for "Apply Changes" option is missing which allows Instant Run. There is another option called "Update Running Application" which does not provide the same functionality.
This option was available in older versions like 3.1 as seen in the screenshot
I am unable to use Instant Run feature in version 3.3.
Is there a workaround for this?
It has been fixed in Android Studio 3.3.2, but you have to (re)define the shortcut yourself (at least for the default Mac OS X Keymap).
Please use CTRL+F10. The keymap doesn't work in android studio 3.3
Update Running Application is same as Apply Changes
You can use same shortcuts CTRL+F10
Thank you.
来源：https://stackoverflow.com/questions/54420094/instant-run-missing-in-android-studio-3-3