It could be something as big as Jena or something smaller. Do you know anything?
Most people use rdflib, but that focuses on RDF, not OWL.
What looks to be the only current and active open source package:
This is a Java package but it has a Python console (via Jython):
A commercial package that has python support:
Some packages that are admittedly incomplete:
Some older packages that appear inactive:
Here is a similar question at answers.semanticweb.com: Python OWL2 API which references this one: Is there a tool for reading functional owl syntax in Python? . Answers to both of them mention InfixOWL which is a part of FuXi.
FuXi does not support RDFLib 3, but there is a ticket as well as some active effort for making that happen. If you wish to use FuXi right away, you can always switch from RDFLib to layercake ("an RDFLib fork readily compatible with FuXi").
来源：https://stackoverflow.com/questions/1719812/is-there-a-python-library-to-handle-owl