The second clause does not need a !variable.nil? check—if evaluation reaches that point, variable.nil is guaranteed to be false (because of short-circuiting).
This should be sufficient:
variable = id if variable.nil? || variable.empty?
If you're working with Ruby on Rails, Object.blank? solves this exact problem:
An object is blank if it’s false, empty, or a whitespace string. For example, "", " ", nil, [], and {} are all blank.