how can I sum the values in column \'two\' based on the items in column \'one\' in pandas dataframe:
df = pd.DataFrame({\'One\': [\'A\', \'B\', \'A\', \'B\'], \'         
        The trick is use pandas built-in functions .groupby(COLUMN_NAME) and then .sum() that new pandas object
import pandas as pd
df = pd.DataFrame({'One': ['A', 'B', 'A', 'B'], 'Two': [1, 5, 3, 4]})
groups = df.groupby('One').sum()
print(groups.head())
You need to group by the first column and sum on the second.
df.groupby('One', as_index=False).sum()
  One  Two
0   A    4
1   B    9