NULL is a special value in RDBMS that means an unknown or inapplicable value.
So nothing will ever be = NULL; such comparison is not valid, thus any queries with expr = NULL in their WHERE clause will return no rows.
Of course this has its quirks and some implementations do things differently; eg: Oracle treats empty strings ('') as NULL and gets quite a bit grief for that.
SQL Server has the ANSI NULL parameter that makes it compliant with SQL-92 (eg comparisons with NULLs like you did won't work.