Try this:
function File(data){
this.data = data;
var self = this;
this.update = function (callback){
var set = function(ajaxData){
self.data = ajaxData.PcbFile;
}
getPcbFile(data.id, function(ajaxData){
set(ajaxData);
callback();
});
};
}
The value of this within a function depends on how that function is called. E.g., when you use the "dot" notation, someObj.someMethod() then within someMethod() you'd have this set to someObj. You can explicitly set this to some other object using the .apply() or .call() methods. Otherwise if you call a function as with set(ajaxData) then this will be the global object (window).
By keeping a reference to this outside your function (I prefer the variable name self for this purpose) you can reference it inside your function.