Can I map a hostname *and* a port with /etc/hosts? [closed]

Answer 1

If you really need to do this, use reverse proxy.

For example, with nginx as reverse proxy

server {
  listen       api.mydomain.com:80;
  server_name  api.mydomain.com;
  location / {
    proxy_pass http://127.0.0.1:8000;
  }
}

Answer 2

No, that's not possible. The port is not part of the hostname, so it has no meaning in the hosts-file.