Very often, I draw graphs in R and export them in pdf or svg. Then I import them in Inkskape or Illustrator. Sometimes this generates weird results. For instance, when I gen
This is a symptom of different fonts being used as the plotting symbols. Try creating the PDF file using:
   pdf("test.pdf", useDingbats = F) 
   plot(1:10, 10:1, pch=16 )
   dev.off()
Screenshot from Inkscape

There is a long "Note" in ?pdf about why the authors of R think some pdf viewers (apparently Inkscape being one such)  are failing  and some configuration suggestions which I have not tested on my Mac.