Does SignalR work with HTTPS?
I have a site on SSL and I want to use SignalR. Is it possible?
If so, do I need to write something different / add configuration
Yes it does! If you're talking about self host: https://docs.microsoft.com/en-us/archive/blogs/jpsanders/how-to-walkthrough-using-httplistener-or-http-server-unmanaged-code-c-as-an-ssl-simple-server
If you're using IIS: http://www.iis.net/learn/manage/configuring-security/how-to-set-up-ssl-on-iis
SSL is a host concern, not really related to SignalR.