In Eclipse I can only run/debug my project by using one of the menu buttons. Pressing F11 or Ctrl + F11 does nothing. I\'ve mapped Debug Las
Please check if another program is trying to hook keyboard messages. Maybe that program prevents the Eclipse to receive some keystrokes including Ctrl + F11. I had this problem and finally I found out that the problem is about my dictionary application which used Ctrl + F11 to popup. After disabling the hotkey in the dictionary application, Eclipse started to handle Ctrl + F11 correctly!
If you use the default key mappings, restoring defaults might work.
Window | Preferences | General | Keys (or Ctrl+Shift+L then L), then hit Restore Defaults and OK.
For custom mappings, I recommend this answer.