When opening an already existing solution in Visual Studio, it says
The C# project \"...\" is targeting \".NETFramework,Version=v4.5.2\", which is not
I had the same issue. When I loaded the project it always asked for the .NET framework 4.5.2 and I was not able to install it because it always said that it was already there.
What worked for me was to install the Microsoft .NET Framework 4.5.2 Developer Pack from https://www.microsoft.com/en-us/download/details.aspx?id=42637
Give it a try. It may work for you as well.
You need to download the .NET Framework 4.5.2 Developer Pack That link compile all the frameworks in one place
http://scottge.net/2015/07/04/a-complete-list-of-microsoft-sdks-for-download/