Does anyone know if it is possible to tell if a specific property on an object is dirty (i.e. the property is different to the one stored on the DB) using NHibernate?
<That is not currently available through the nHibernate (or Hibnernate, AFAIK) API. You could write something like this yourself by storing the state of the objects when they're loaded into session, then compare them.
NOTE: I haven't seen this for myself, but, if you haven't locked into an ORM choice, you should look at Subsonic. A lot of the dirty status is tracked within the objects themselves, and you'd be able to determine if a particular property is dirty.