Use regex in list within a dataframe in pandas

Question

Hello I have a df such as :

COL1 COL2 COL3 
G1   3    [[(\'A_+__SP3\', \'B_-__SP3\'), (\'A_+__SP4\', \'C_-__SP3\'), (\'B_+__SP3\', \'D_+__SP5\'),(\'A_+__SP4\'