I am learning Python from Coursera. In this course they use SimpleGUI module on CodeSkulptor. Can anyone tell me how to integrate SimpleGUI with python 2.7
I don't see any information on PyPI about which versions of Python simpleGUI supports. You can just try running it with Python 3 and see what happens. If it doesn't work, try using the 2to3 tools: http://docs.python.org/2/library/2to3.html
Note that simpleGUI is based on Tkinter. I would recommend learning a full GUI toolkit like Tkinter, wxPython or PySide rather than a derivative.