It's really tough to handle a 4G file as such. I used to handle larger text files, but I never used to load them in to my editor. I mostly used UltraEdit in my previous company, now I use Notepad++, but I would get just those parts which i needed to edit. (Most of the cases, the files never needed an edit).
Why do u want to load such a big file in to an editor? When I handled files of these size, I used GNU Core Utils. The most common operations i performed on those files were head ( to get the top 250k lines etc ), tail, split, sort, shuf, uniq etc. It's really powerful.
There's a lot of things you can do with GNU Core Utils. I would definitely recommend those, instead of a new editor.