I\'m using Virtualenv with profit on my development environment with web.py, simplejson and other web oriented packages.
I\'m going to develop
It should be enough to create an empty virtualenv and then copy the contents of the .../site-packages/PyQt4 directories into it.
I suggest to install PyQt4 once globally, make a copy of the directory, uninstall it and then use this trick to create VEs.
I asked if it's possible to install PySide from within virtualenv on irc.freenode.net #pyside channel and got positive answer from hugopl. So I followed instructions from PySide Binaries for Microsoft Windows and it worked. The output is below.
Z:\virtualenv\pyside>Scripts\activate.bat
(pyside) Z:\virtualenv\pyside>where python
Z:\virtualenv\pyside\Scripts\python.exe
(pyside) Z:\virtualenv\pyside>easy_install PySide
install_dir Z:\virtualenv\pyside\Lib\site-packages\
Searching for PySide
Reading http://pypi.python.org/simple/PySide/
Reading http://www.pyside.org
Reading http://www.pyside.org/files/pkg/
Best match: PySide 1.0.0beta1qt471
Downloading http://www.pyside.org/files/pkg/PySide-1.0.0beta1qt471.win32-py2.6.exe
Processing PySide-1.0.0beta1qt471.win32-py2.6.exe
Deleting c:\users\piotr\appdata\local\temp\easy_install-fvfa7e\PySide-1.0.0beta1qt471-py2.6-win32.egg.tmp\EGG-INFO\scripts\py
ide-uic-script.py
Deleting c:\users\piotr\appdata\local\temp\easy_install-fvfa7e\PySide-1.0.0beta1qt471-py2.6-win32.egg.tmp\EGG-INFO\scripts\py
ide-uic.exe
creating 'c:\users\piotr\appdata\local\temp\easy_install-fvfa7e\PySide-1.0.0beta1qt471-py2.6-win32.egg' and adding 'c:\users\
iotr\appdata\local\temp\easy_install-fvfa7e\PySide-1.0.0beta1qt471-py2.6-win32.egg.tmp' to it
creating z:\virtualenv\pyside\lib\site-packages\PySide-1.0.0beta1qt471-py2.6-win32.egg
Extracting PySide-1.0.0beta1qt471-py2.6-win32.egg to z:\virtualenv\pyside\lib\site-packages
Adding PySide 1.0.0beta1qt471 to easy-install.pth file
Installing pyside-uic-script.pyc script to Z:\virtualenv\pyside\Scripts
Installing pyside_postinstall.py script to Z:\virtualenv\pyside\Scripts
Installing pyside_postinstall.pyc script to Z:\virtualenv\pyside\Scripts
Installing pyside-uic-script.py script to Z:\virtualenv\pyside\Scripts
Installing pyside-uic.exe script to Z:\virtualenv\pyside\Scripts
Installed z:\virtualenv\pyside\lib\site-packages\pyside-1.0.0beta1qt471-py2.6-win32.egg
Processing dependencies for PySide
Finished processing dependencies for PySide
(pyside) Z:\virtualenv\pyside>python Scripts\pyside_postinstall.py -install
Generating file Z:\virtualenv\pyside\Scripts\qt.conf...
The PySide extensions were successfully installed.
Let's assume your virtualenv is named myProject and you're using virtualenvwrapper. A Unix platform is also assumed.
$ workon myProject
$ pip install --no-install SIP
$ pip install --no-install PyQt
$ cd ~/.virtualenvs/myProject/build/SIP
$ python configure.py
$ make
$ make install
$ cd ~/.virtualenvs/myProject/build/PyQt
$ python configure.py
$ make
$ make install
$ cd && rm -rf ~/.virtualenvs/myProject/build # Optional.
If you installed pyqt via brew on a Mac (specifically I'm on Mavericks):
ln -s /usr/local/Cellar/sip/4.15.2/lib/python2.7/site-packages/*.* ~/{VIRTUALENVHOME}/{VIRTUALENVNAME}/lib/python2.7/site-packages
ln -s /usr/local/Cellar/pyqt/4.10.3/lib/python2.7/site-packages/PyQt4/ ~/{VIRTUALENVHOME}/{VIRTUALENVNAME}/lib/python2.7/site-packages/PyQt4
pip install pygments pyzmq
Of course those version folder numbers may change over time.
What worked for me was copying /PyQt4/ and sip.x86_64-linux-gnu.so from /usr/lib/python2.7/dist-packages to <VIRTUALENV>/lib/python2.7/site-packages and changing the ownership permissions on these copied files (since the copies were owned by root).
Try this one: pip install python-qt5