HTTP error 500.19 - Cannot read configuration file

Question

In one of my ASP.NET apps, all of a sudden I am unable to run it in Visual Studio 2013 due to the error displayed below. It appears that it is trying to open the web.config from

Answer 1

After all this answers I find my solution. Delete te WebSite in the IIS and recriate. Why? Because I had create de website before installed the framework 4.5 and URL Rewrite.