I\'m using this shell command to make thumbnail from VIDEO_FILE from 123 second and save it to THUMBNAIL_FILE.
ffmpeg -i VIDEO_FILE -r 1 -ss 123 -f image2 THUMB
Ffmpeg is not really good with creating thumbnails as I investigated. People recommend to use mplayer (by ffmpeg creators).
mplayer VIDEO_FILE -ss 00:10:11 -frames 1 -vo jpeg:outdir=THUMBNAILS_DIRECTORY