While creating the new table in the SQL Server Management Studio, Please refer to the below mentioned screen shot for adding the description to a column.

Another way to do it programatically
EXEC sp_updateextendedproperty
@name = N'MS_Description', @value = 'Your description',
@level0type = N'Schema', @level0name = dbo,
@level1type = N'Table', @level1name = Your Table Name,
@level2type = N'Column', @level2name = Yuur Column Name;