I just upgraded from SSMS 2005 to 2012. Previously, I could hit CTRL+R and the Query Results windows would disappear.
After I upgraded to SSMS I r
In Microsoft SQL Server Management Studio v18.2 (aka. SSMS 18) you might want to try resetting keyboard mapping scheme in Options -> Environment -> Keyboard -> Keyboard window by clicking Reset button at the top of it with (Default) selected in option list.
Before resetting, it had only one option which processed Ctrl+R press only in DMX Query Editor:
After resetting it showed more options which included SQL Query Editor:
After that, key shortcut works(Windows 10 1809 x64).