I am working with PyCharm 4.04. Since I installed it, every time I open it, as default directory I get this:
C:\\Users\\Laura\\AppData\\Local\\Temp\\main.
Another solution is to close the project, run rm -rf .idea and re-open it. Apparently Pycharm gets confused by some direct folder manipulation and doesn't reflect it properly in his .idea/*.xml files
rm -rf .idea
.idea/*.xml