Insertion sort has a runtime that is Ω(n) (when the input is sorted) and O(n2) (when the input is reverse sorted). On average, it runs in Θ(n2
Most algorithms have average-case the same as worst-case. To see why this is, let's call O the worst-case and Ω the best-case. Presumably, O >= Ω as n goes to infinity. For most distributions, the average case is going to be close to the average of the best- and worst-case - that is, (O + Ω)/2 = O/2 + Ω/2. Since we don't care about coefficients, and O >= Ω, this is the same as O.
Obviously, this is an oversimplification. There are running time distributions that are skewed such that the assumption of the average-case being the average of the worst-case and the best-case is not valid*. But this should give you a decent intuition as to why this is.
*As mentioned by templatetypedef in the comments, some examples are quicksort/quickselect, BST lookup (unless you balance the tree), hash table lookup, and the simplex method.