I would suggest getting a good editor so that you don't get bitten by whitespace. For simplicity, I just use ActivePython's packages Link, which include an editor and all of the win32api libraries. They are pretty fun to get into if you have been using C#. The win32api in Python can be a little bit simpler. You don't need to do the whole DDLImport thing. Download ActivePython (which comes with CPython), open it up, and start entering some stuff at the console. You will pick it up fairly easy after using C#. For some more interesting Python tidbits, try ActiveState code, which has all sorts of recipes, which can allow you to very simply see different things that you can do with Python.
