I have a Django app working with uWSGI. My uWSGI config is:
[uwsgi]
http = 127.0.0.1:8000
env = DJANGO_SETTINGS_MODULE=my_django_app.settings
module = my_dja
[uwsgi]
base = /var/www/html/poopbuddy-api
chdir = %(base)
app = app
I don't exactly know what chdir does, but I think it fixed it... I'm guessing it at least sets the default location to the app's root folder. Something like this also happens to me when I'm using PyCharm, I have to set "working directory" from the "Edit Configurations" or "edit/debug configuration" window.