Given following data, what is the best way to organize an array of elements so that the fastest random access will be possible?
Each element has some int number,
The first one is probably faster, since memory access latency will be the dominant factor in performance. Ideally you should access memory sequentially and contiguously, to make best use of loaded cache lines and reduce cache misses.
Of course the access pattern is critical in any such discussion, which is why sometimes it's better to use SoA (structure of arrays) and other times AoS (array of structures), at least when performance is critical.
Most of the time of course you shouldn't worry about such things (premature optimisation, and all that).