I need to write a variadic macro in C which must take zero or more arguments.
In gcc, that can be achieved by adding \"##\" after the comma, e.g. ,##____VA_ARG
Yes, gcc swallowing the comma is non standard and you should not rely on that.
With C99 conforming preprocessors you may achieve a similar effect by testing for a macro arguments that is the empty token. For the ideas of how this works you could see here, for a whole set of preprocessor macros that ease the programming of such features there is P99.