My web-site has AJAX-powered search, that uses deep-linking. When user follows a link …
http://example.com/articles#/?tags=Mac%20OS,review
@NickFitz is correct, but if you must send whatever comes after the # hash/pound symbol, you can use the URL encoded characters that represent # which is %23.
So %23 and whatever that comes after %23 will be sent to the server. If you are using modern web server, they will automatically recognize that %23 is #. In Ruby on Rails, Rack does this for you.