Recently, the SourceSafe integration into visual studio has started to perform badly because we have moved, and the SourceSafe \"server\" is located across a VPN which goes
HKEY_CURRENT_USER\Software\Microsoft\DevStudio\6.0\Source Control\Disabled
I followed this and it seemed to work upon trying it again. I think I might've had a second copy of visual studio running when I did it the first time.