I have just upgraded to VS 2010, and I have performance problems which I did not have before (in VS 2008).
The most annoying thing is that it freezes while I work in
An old post I know, but in case it helps others (as the previous answers focused on source code)...
I found that it wasn't my source code that was the issue, that was held locally along with all the references, but the default locations (project, project templates and item templates) as these were held on a networked drive. These can be altered in the Tools -> Options -> Projects and Solutions
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Alternatively you could change the frequency of the saves or turn them off altogether via Tools -> Options -> AutoRecover