I\'m looking for your best solutions for creating a new message instance based on a pre-defined XSD schema to be used within a Biztalk orchestration.
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To create a new message you can simply create a new System.Xml.XmlDocument and assign that to a message variable. You can use it's Load or LoadXml methods to load the required content that conforms to the schema.
System.Xml.XmlDocument
Load
LoadXml