I want to create a simple LOCAL web app in Python.
The web server and \"back-end\" code will run on the same system (initially, Windows system) as the UI. I doubt it
Any framework will do this. Django certainly will do, but since you want something smaller, I'd recommend will BFG/Pyramid, which is very lightweight, extremely extensible and flexible and fun to use. But there are loads of others, and as mentioned, the built in wsgiref is as lightweight as you get. :-)