I have a very large CSV File with 100 columns. In order to illustrate my problem I will use a very basic example.
Let\'s suppose that we have a CSV file.
As Wai Yip Tung said, you can filter your dataframe while reading by specifying the name of the columns, for example:
import pandas as pd data = pd.read_csv("ThisFile.csv")[['value','d']]
This solved my problem.