I am using editable pdf files (created by Nitro PDF Software) in my application. These pdf files have a lot of editable fields (like textboxes) and one button (like submit).
From Wikipedia, PDF Interactive elements there are two possibilities for integrating data and PDFs (there are also links to the specifications):
For compatibility issues I would go for AcroForms. In that case I would use XFDF, because it is XML and therefore easier to parse. I never used Nitro, but when you build a PDF form you usually provide a "Save" button and choose at action for this button "Send/Post form to server" with the data format XML which is just XFDF.
This works only when the PDF is viewed in the browser. So the typical use case is: have an empty PDF template on the server, before returning the PDF to the user mix your data into the PDF, the user enters data in the form (PDF is opened in the browser via a plugin or natively in Chrome), then the user presses the save buttons which posts a xml on the server. The next time the user asks for his PDF, you took the recent data and mix it again with the template.
So only two questions are open:
See the complete process here: http://itextpdf.com/book/chapter.php?id=9 . This example updates the PDF with the form dynamically at run time. Since iText is used there is no difference between Java and C#.
Be aware that previous versions of iText (Java up to 2.1.7 and C# up to 4.1.6) were distributed under the Mozilla Public License or the LGPL, while current versions are distributed under the Affero General Public License. Thats explains why the older versions are still used.