I have an ASP.NET MVC project, with an ASP.NET web api defined as an area in this project. So the structure is the following:
MVC Web
Controllers
View
Possible solution: I had forgotten that I was previously doing some remote debugging and had set debug symbols to be loaded from a UNC path instead of the Microsoft Symbol Servers.
To fix this head to: Tools -> Options -> Debugging -> Symbols -> Make sure 'Microsoft Symbol Servers' is checked.
I also found this issue from creating a new Solution Configuration and not basing it on any existing configuration, such as the DEBUG configuration. That caused Debug Info to be set to none.
To fix this: Right-click your project -> Properties -> Build -> Make sure your faulty Solution Configuration is set -> click Advanced -> change Debug Info to full.