I previously had Conda running smoothly on Mojave, but I\'ve found that the upgrade to Catalina moves the \"anaconda3\" folder to your Desktop > Relocated Items > Security >
No solution will be completely working without fixing the baked-in hard-coded prefix entries in files. There's a longer description and a recommended fix at https://www.anaconda.com/how-to-restore-anaconda-after-macos-catalina-update/