I have a matrix data with m rows and n columns. I used to compute the correlation coefficients between all pairs of rows using np.corrcoef:
If you do not have to use pearson correlation coefficient, you can use the spearman correlation coefficient, as it returns both the correlation matrix and p-values (note that the former requires that your data is normally distributed, whereas the spearman correlation is a non-parametric measure, thus not assuming the normal distribution of your data). An example code:
from scipy import stats
import numpy as np
data = np.array([[0, 1, -1], [0, -1, 1], [0, 1, -1]])
print 'np.corrcoef:', np.corrcoef(data)
cor, pval = stats.spearmanr(data.T)
print 'stats.spearmanr - cor:\n', cor
print 'stats.spearmanr - pval\n', pval