Regions must never be used inside methods. They may be used to group methods but this must be handled with extreme caution so that the reader of the code does not go insane. There is no point in folding methods by their modifiers. But sometimes folding may increase readability. For e.g. grouping some methods that you use for working around some issues when using an external library and you won't want to visit too often may be helpful. But the coder must always seek for solutions like wrapping the library with appropriate classes in this particular example. When all else fails, use folding for improving readibility.
