I have a major problem with project configurations. Everything started when I wanted to add new solution configuration (named \"Dev_WithSource\") based on existing \"De
I know this is an old thread, but this was the answer for me:
In the Configuration Manager, select "Edit..." in the "Configuration" column for each project (not via the dropdown named Active solution configuration) that has configurations you want to remove.
In the dialog that pops up, mark each unwanted configuration and select "Remove".
Copied from How do I remove a project configuration in Visual Studio 2008?