is it possible to force any communication from e.g. Javascript/JQuery to any serial comport?!
google is not able to answer that question.. but anyway it should be po
kimstik's suggestion, using the jUART plugin for the browser is an excellent solution.
Another possibility is to use a middleware, that facilitates the serial communication and provides a web interface, that JavaScript can interface with using AJAX requests.
Python could be used, e.g. a script using a combination of pySerial and python-bobo.