WPF MVVM: Binding a different ViewModel to each TabItem?

Question

I have a main window with a tab control containing 2 tabItems:

I currently

Answer 1

I use a framework such as Prism, that allows you to define regions and use the RegionManager. You can then define a ContentControl as the 'ui' for the TabItem

Then you can use the RegionManager.RequestNavigate to populate a named region with a particular view (and our views import a viewmodel and set their datacontext).