Visual Studio incredibly slow when renaming files

Question

I have a medium-sized solution with 99 projects that has recently started behaving weirdly:

1) If I try to rename a file through the solution explorer, VS will seem

Answer 1

When testing I'd made an attempt at setting up one of the projects to build on a different server, both in Debug and Release mode. I though I'd cleaned up both, but apparently I'd only done so under the Debug configuration.

Apparently meanwhile that server has decided it hates my machine, which makes my machine freeze while waiting for it.

Closing Visual Studio and manually editing the .csproj file solved the problem.