"IDE" isn't a very well defined term, but in my experience single unit IDEs (as opposed to editor + added plugins) seem to have more powerful debuggers, more integration between different tools in the IDE (e.g. easy to debug unit tests, use of deep code analysis to feed autocompletion, etc). And of course more things work out of the box w/o having to download and configure plugins yourself, and the GUI is often are easier to figure out for new users or novices. But it's a personal choice and the bottom line is you should try the tools you're considering and choose the one that fits best with your needs.
