I have a table which has a header row, but also a header column and a total column with several columns in between.
Something like this:
Name Scor
Can I propose a somewhat unorthodox solution?
What would you think about placing the 'total' column after the 'name' column, rather than at the very end? Wouldn't this avoid the requirement for only a portion of the table to scroll?
It's not exactly what you're asking for, but perhaps it is a sufficient solution, given that the alternative would be pretty messy. (Placing the 'total' and 'name' columns outside of the table, for instance, would create alignment problems when not all rows are of equal height. You could correct this with javascript but then you'd be entering a whole new world of pain).
Also from a UI perspective, it may be that 'name' and 'total' are the most important data, in which case it would make sense to put them together, followed by a sort of 'breakdown' of the total. Of course, we seem to have an intuition that a 'total' should come after its constituent parts, but I don't think it would cause too much confusion to the user if the order were reversed like this (though this is a question for you, based on your product and your users).
Anyway, something to consider.
EDIT:
Here are some more unorthodox solutions, now that I think I understand your intentions a bit better:
Anyway you get the idea. Perhaps it is better to look for a UI solution than a contorted markup solution. Ultimately I would be questioning how important it is to present so much data to the user at once, that a portion of it needs to scroll in a particular fashion for the data to be readable. Perhaps you're building a spreadsheet app, and you really do need to display a 100x100 matrix in a single view. If not, you could surely come up with more creative ways than I have to split up the results.