I\'ve currently got a spreadsheet type program that keeps its data in an ArrayList of HashMaps. You\'ll no doubt be shocked when I tell you that this hasn\'t proven ideal.
Assuming all your rows have most of the same columns, you can just use an array for each row, and a Map
If Strings are often repeated, you could use a String pool to reduce duplication of strings. Object pools for other immutable types may be useful in reducing memory consumed.
EDIT: You can structure your data as either row based or column based. If its rows based (one array of cells per row) adding/removing the row is just a matter of removing this row. If its columns based, you can have an array per column. This can make handling primitive types much more efficent. i.e. you can have one column which is int[] and another which is double[], its much more common for an entire column to have the same data type, rather than having the same data type for a whole row.
However, either way you struture the data it will be optmised for either row or column modification and performing an add/remove of the other type will result in a rebuild of the entire dataset.
(Something I do is have row based data and add columnns to the end, assuming if a row isn't long enough, the column has a default value, this avoids a rebuild when adding a column. Rather than removing a column, I have a means of ignoring it)