Failed to launch simulated application: Unknown error

Question

• OS X 10.5.7 (genuine Mac)
• Xcode 3.1.3
• iPhone SDK 3.0

When I try to execute my iPhone application in simulator, I get the dreaded error

Answer 1

Looks like this is your key bit (doesn't normally come up in system log):

VoiceOverTouch exiting because accessibility is not enabled. To enable do this: 
'defaults write com.apple.Accessibility AccessibilityEnabled true' 

Your app has some dependency on accessibility being enabled. Suggest you follow the instruction and run the bit in quotes on your system console.