Do you have to deploy the .pdb file with compiling under release?
Why does it even compile a .pdb when you do a release build anyway?
Nope. You don't need to distribute them. It'll help with debugging (or I should say it will make debugging possible for sane people).
You can also turn off or adjust the 'level' of symbols generated in Visual Studio -- just go to Project Properties / 'Build' tab / 'Advanced' -- and make adjustments to the 'Debug info' field.