I searched hard, but was unable to grasp the whole idea. Can anyone tell me:
10,000 foot view:
COM is the communication mechanism for software components. Example, you can interact with COM interfaces (COM interop in .NET) to use functionality not exposed through a common interface (.NET assembly).
GUIDs are explained fairly decent on Wikipedia http://en.wikipedia.org/wiki/Globally_Unique_Identifier
I always understood LIB files to be object files for the C++ linker. They contain the code for all objects in a cpp file. The compiler optimizes when it links disregarding portions of the object file that it doesn't need.
Someone please clarify as I am sure I butchered some of this.