I would like to start answering on your question with the new one: What your class Gene is responsible for? May be you have heard about the 'Single-Responsibility Principle': A class should have only one reason to change. So, I believe if you answer this question you will be able to decide how your application should be designed. In this particular case, I would not use neither the first approach nor the second one. In my opinion it is much better to define new responsibility and encapsulate it in a separate class or may be a function.
